Construction and Preliminary Application of High Resolution Microendoscopy Imaging System

High Resolution Microendoscopy (HRME) is a new imaging method which based on high resolution fiber and molecular imaging technology and it is possible to organize real-time imaging. After design and optimization of excitation light conduction part, fluorescent image transfer unit, optical fast switching unit and image capture unit, we constructe a HRME imaging system. We make an imaging observation of animal gastrointestinal tract by using HRME system and the results show that the feasibility of virtual pathology of HRME which lay the foundation for further clinical research. As an instant histopathological imaging method, HRME is expected to become a new immediate diagnosis model.