用于肿瘤消融边界监测的电阻抗成像系统设计与实验研究

      Design and Experimental Study of Electrical Impedance Tomography System for Tumor Ablation Boundary Monitoring

      • 摘要: 微创热消融技术不同于传统外科手术,需要借助辅助设备对消融结果进行评估,而目前临床上采用的超声和CT又存在伪影和辐射等不足之处。为此,该文提出并设计了一款基于电阻抗成像技术的微创热消融评估系统,用于监测消融范围大小。同时,在电阻抗成像系统设计上创新性地引入可程控放大的前馈信号作为乘法解调器的参考信号,能够有效解决微弱信号淹没在噪声中的问题,提高成像精度。系统通过STM32控制电流信号的激励大小和边界电压的采集与处理,将采集的数据上传至上位机,再由Newton-Raphson算法重构电导率分布,从而映射出消融区域范围。实验测试结果表明,该系统可以有效地反映微波消融区域大小。在同样的微创消融参数下,平均成像长径误差为0.6 mm,短径误差为0.8 mm,轴比(长径/短径)误差为1.75%,具有较高的一致性,验证了电阻抗成像在微创热消融下的技术前景。

         

        Abstract: The minimally invasive thermal ablation technology differs from traditional surgical operations, which requires auxiliary equipment to evaluate ablation results. However, the ultrasound and CT currently used in clinical practice have shortcomings such as artifacts and radiation. Therefore, this paper proposes a design for a minimally invasive thermal ablation evaluation system based on the principle of electrical impedance tomography technology to monitor the ablation range. At the same time, the innovative introduction of a programmable gain feedforward signal as the parameter signal of the multiplier demodulator in the electrical impedance tomography system design can effectively solve the problem of weak signals being submerged in noise and improve imaging accuracy. The system controls the amplitude of the excitation current signal and the acquisition / processing of boundary voltages via an STM32, uploads the collected data to an upper computer, and reconstructs the conductivity distribution using the Newton-Raphson algorithm to map the size of the ablation area. Experimental results show that the system can effectively reflect the size of the microwave ablation area. Under the same minimally invasive ablation parameters, the average imaging errors are 0.6 mm for the long diameter, 0.8 mm for the short diameter, and 1.75% for the axial ratio (long diameter / short diameter), demonstrating high consistency. This verifies the technical potential of electrical impedance tomography in minimally invasive thermal ablation.

         

      /

      返回文章
      返回