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      锥形束CT图像用于盆腔肿瘤剂量计算准确性评估

      Accuracy Assessment of Cone-Beam CT Images for Pelvic Tumor Dose Calculation

        摘要
      • 摘要:
        目的 评估锥形束CT（cone-beam CT, CBCT）图像在盆腔肿瘤放疗剂量计算中的可行性和准确性。
        方法  采用改进容积密度覆盖法建立CBCT图像的CT值－相对电子密度（relative electron density, RED）曲线，将定位CT计划移植至CBCT图像上，在优化参数不变的情况下，CBCT计划使用构建的密度曲线计算剂量，比较两种计划的剂量计算偏差。
        结果 两种计划的靶区和危及器官（organ at risk, OAR）各项剂量学参数平均差异分别小于1%和1.5%，靶区适形性指数（conformity index, CI）、均匀性指数（homogeneity index, HI）以及伽马通过率均较为接近，差异均无统计学意义。
        结论 经该方法修正后的CBCT图像可用于盆腔肿瘤放疗计划剂量计算。

         

        Abstract:
        Objective To evaluate the feasibility and accuracy of cone-beam CT (CBCT) images for radiotherapy dose calculation in pelvic tumors.
        Methods An improved volumetric density coverage method was used to establish CT value-relative electron density (RED) curves for CBCT images. The planning CT plans were transferred to the CBCT images, and the constructed density curves were applied to calculate doses for CBCT plans while maintaining the optimization parameters unchanged. Dose calculation deviations between the two plans were analyzed.
        Results The mean differences in dosimetric parameters for the target volume and organs at risk (OAR) between the two plans were less than 1% and 1.5%, respectively. The target conformity index (CI), homogeneity index (HI), and gamma passing rates were highly consistent, with no statistically significant differences.
        Conclusion CBCT images corrected by this method can be used for dose calculation in pelvic tumor radiotherapy planning.

         

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