Abstract: By studying the current situation of multi-agent collaborative innovation and clinical achievements transformation at home and abroad, it is clear that multi-agent collaborative innovation is the only way for clinical research achievements transformation under the current background. This paper proposes a set of transformation path of clinical research achievements based on the multi-agent collaborative innovation platform of “production, teaching, research and medicine”, which is supported by policy guidance and innovation management, and explore the role of equipment management department in achievement transformation.