Abstract: Objective To explore the application effect of the team resource management (TRM) mode in the management of the secondary warehouse of medical consumables in the operating room based on the support of smart healthcar. Methods Using the TRM management method， a new mode of intelligent management of medical consumables in the operating room was implemented to form a complete closedloop management process of medical consumables through the unique identification (UDI) and radio frequency identification (RFID) scanning technology of smart medical. Results The average purchase amount of high-value consumables for each operation in the operating room of the hospital decreased by 6.2%, the proportion of low-value consumables used decreased by 32%, and the efficiency of supplier distribution increased by 11.7% in 2021. The cumulative reduction in medical costs is more than 40 million CNY. Conclusion Based on the new management model of the secondary warehouse of medical consumables in the operating room by using the TRM method under the support of smart healthcare, the team cooperation has been strengthened, and the management level of medical consumables in the operating room has been effectively improved.