Abstract: This study analyzes the difference between non-invasive and invasive pelvic floor electric stimulation therapeutic apparatus. Through establishing the resistance network model of human pelvic floor muscle group, using circuit loop analysis and simulation, the current and voltage distribution are obtained, and the conclusions are listed as follows: Since invasive electrode has a central symmetry, pelvic floor muscles have equipotential areas and unable to form the current loop. Non-invasive electrodes don’t have this problem. With the same stimulation conditions, non-invasive stimulation intensity of the superficial pelvic floor muscle is the highest, followed by the middle and the deep layer. While the invasive electrode stimulates the superficial and deep pelvic floor muscles moderately, the middle pelvic floor muscles some parts strongly, some parts weakly. The results of in vitro experiments show that the tissue impedance is very small, and the non-invasive electrical stimulation is well conducted into the tissue, which is consistent with the analysis and simulation results.