用于消化内镜下组织夹闭的磁吻合系统的设计

Design of Magnamosis System for Endoscopic Tissue Clamping

摘要: 该文基于磁吻合技术原理，提出了用于消化内镜下组织夹闭的磁吻合系统的设计。该系统包括半环状磁体、特殊结构的透明帽以及可拆卸推杆，借助现有消化内镜和内镜下组织抓钳，可完成内镜下对出血或穿孔部位组织的严密夹闭吻合，吻合完成后磁体自行脱落并经消化道排出体外。动物实验表明，该系统使用方便，瘘口夹闭牢靠，磁体排出时间7~21 d，未出现磁体滞留及消化道梗阻。进一步进行安全性验证、优化内镜下操作，该系统可在临床试用。

Abstract: Based on the principle of magnetic anastomosis technique, the design of magnetic anastomosis system for endoscopic tissue clamping is proposed. The system includes a semi-ring magnet, a special structure transparent cap and a detachable push rod. With the help of the existing digestive endoscopy and endoscopic tissue gripper, the endoscopic close clamping and anastomosis of the bleeding or perforated tissue can be completed. After the anastomosis, the magnet falls off and is discharged through the digestive tract. Animal experiments showed that the system was easy to use, the fistula was clamped firmly, the magnet was discharged for 7~21 days, and there was no magnet retention and digestive tract obstruction. Further safety verification, optimization of endoscopic operation, the system can be used in clinical trial.