肝脏常温机械灌注修复及评估系统的研制

Development of Liver Normothermic Machine Perfusion Repair and Assessment System

摘要: 介绍了一种肝脏常温机械灌注修复及评估系统。系统由肝脏常温氧合机械灌注装置、荧光成像系统及组织测氧仪组成。常温氧合机械灌注装置可对供肝进行持续灌注并实时监测调控灌注参数，荧光成像系统通过识别肝脏代谢的吲哚菁绿来评估供肝微循环情况及肝细胞代谢功能，组织测氧仪可实时监测肝组织氧分压变化评估细胞耗氧状态。

Abstract: This paper introduced a liver normothermic machine perfusion repair and assessment system. This system consists of a liver normothermic machine perfusion device, a fluorescence imaging system and a tissue oxygen detector. The normothermic machine perfusion device can continuously perfuse the donor liver and monitor and control the perfusion parameters in real time. The fluorescence imaging system can detect the indocyanine green metabolized by the liver to evaluate the microcirculation and the metabolism function of hepatocytes. The tissue oxygen detector can monitor the change of oxygen partial pressure of liver tissue in real time to evaluate the state of cell oxygen consumption.