生物可吸收冠状动脉支架发展现状及临床前评价

Bioresorbable Vascular Scaffold: A Focused Review on Development and Preclinical Studies

摘要: 生物可吸收冠状动脉支架是近年来出现的经皮冠状动脉介入治疗的新手段，它作为血管重塑过程的短暂支撑，在血管生理功能恢复后，逐渐消失，使治愈的血管不受束缚，解决了金属裸支架及药物洗脱支架存在的问题，在临床上具有良好的应用前景。该文对生物可吸收冠状动脉支架的发展情况，临床前安全和有效性评价以及存在的问题做了综述。

Abstract: Bioresorbable vascular scaffolds(BVS) are new treatment strategies of percutaneous coronary intervention. They have been introduced to overcome limitations of bare metal stents (BMS) and drug-eluting stents(DES), since they provide temporary scaffolding and then disappear, liberate the treated vessel from cage. In this article, we review the current status and problems of BVS, various tests required before gaining regulatory approval for clinical use.