Abstract: To analyze the current situation about informatization construction of medical device administration in China, including such links of market access of medical device, occupation access of enterprise, risk monitoring of postmarketing, sampling and testing of post-marketing, complaint and inspecting, advertising management and standard management. By the informatization of medical device administration, some supervision problems can be solved, supervision efficiency can be promoted. For accelerating the informatization construction of medical device administration, we should do top-level design and implement by step, pay more attention to the informatization of manufacturing enterprise, product tracing and standard management, in order to continually improve the level of medical device administration.