Abstract: In-stent restenosis is a main problem in the application of stents. It has been proved that rapid endothelialization of stents after implantation is the key point for solving the problem of restenosis. Recent years researchers focus on developing biodegradable magnesium alloy stents. The cytocompatibility is essential for the design of magnesium alloy stents. In this article, recent research about the endothelial cytocompatibility of magnesium alloy was reviewed, including methods, results, shortcomings and advice.