Abstract: Objective To adapt to hospital's modernized construction, we took effect measures to ameliorate disinfection procedure and increase disinfection efficiency for Electronic Endoscopy.Methods Through confirming the character of disinfection procedure for Electronic Endoscopy in conjunction with infection controlling, we investigated the practical administrative mode in hospital for disinfection procedure of Electronic Endoscopy.Results After constantly ameliorating administrative mode for disinfection procedure, the disinfection efficiency under its supervision was significantly increased.Conclusion Reasonable administration and region partition of Electronic Endoscopy disinfection could improve disinfection efficiency in hospital, thus ensuring clinical demand for Endoscopy Center and promoting sustainable development of Department of Internal Medicine.