Abstract: Objective Solve the problems of high cost, low utilization rate of resources, low medical care quality problem in medical consumables material logistics management for scientific of medical consumables management. Methods Analysis of the problems existing in the domestic medical consumables material logistics management in hospital, based on lean management method, SPD(Supply, Processing, Distribution) for specific applications, combined HBOS(Hospital Business Operation System), HIS (Hospital Information System) system for medical consumables material management. Results Achieve the lean management in medical consumables material purchase, warehouse construction, push, clinical use and retrospect. Conclusion Lean management in medical consumables material can effectively control the cost in logistics management, optimize the allocation of resources, liberate unnecessary time of medical staff, improve the quality of medical care. It is a scientific management method.