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离心式磁悬浮血泵溶血性能分析

王义文, 张帆, 方媛, 董百川, 周亮

王义文, 张帆, 方媛, 董百川, 周亮. 离心式磁悬浮血泵溶血性能分析[J]. 中国医疗器械杂志, 2016, 40(3): 169-172. DOI: 10.3969/j.issn.1671-7104.2016.03.004
引用本文: 王义文, 张帆, 方媛, 董百川, 周亮. 离心式磁悬浮血泵溶血性能分析[J]. 中国医疗器械杂志, 2016, 40(3): 169-172. DOI: 10.3969/j.issn.1671-7104.2016.03.004
Wang Yiwen, Zhang Fan, Fang Yuan, Dong Baichuan, Zhou Liang. Hemolysis Performance Analysis of the Centrifugal Maglev Blood Pump[J]. Chinese Journal of Medical Instrumentation, 2016, 40(3): 169-172. DOI: 10.3969/j.issn.1671-7104.2016.03.004
Citation: Wang Yiwen, Zhang Fan, Fang Yuan, Dong Baichuan, Zhou Liang. Hemolysis Performance Analysis of the Centrifugal Maglev Blood Pump[J]. Chinese Journal of Medical Instrumentation, 2016, 40(3): 169-172. DOI: 10.3969/j.issn.1671-7104.2016.03.004

离心式磁悬浮血泵溶血性能分析

详细信息
    作者简介:

    王义文,E-mail:yiwenwang0451@126.com

  • 中图分类号: R318

Hemolysis Performance Analysis of the Centrifugal Maglev Blood Pump

  • 摘要: 对自主研制的离心式磁悬浮血泵,为分析研究其溶血性能,对其内流场进行建模,在Fluent中进行计算流体力学分析;搭建体外溶血实验装置,在设计工况下,测量一定时间间隔内血浆中游离蛋白含量及红细胞压积,计算出血泵的标准溶血指数。数值模拟结果显示血泵整个流道内静压力分布均匀,各流道间过渡平稳;内部壁面剪切力均在150 Pa以下,红细胞发生破坏与暴露时间无关。体外溶血实验得到标准溶血指数NIH值为(0.002 9±0.000 7)mg/L,符合人类生理学要求。
    Abstract: In order to analyze and study the hemolysis performance of the centrifugal maglev blood pump, which was designed by ourselves, this paper built the mathematical model and computational fluid dynamics analyzed it using Fluent. Then we set up the in vitro hemolysis experiment platform, in case of the design condition, the content of free hemoglobin and hematocrit in plasma were measured in a certain time interval, and calculated the normalized index of hemolysis of the blood pump. The numerical simulation results show the internal static pressure distribution is smooth inside the pump, the wall shear stress inside the pump is less than 150 Pa. Therefore, the red blood cell damage and exposure time is independent. The normalized index of hemolysis is (0.002 9±0.000 7) mg/L, which is in accordance with human physiological requirement.
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  • 被引次数: 0
出版历程
  • 收稿日期:  2016-02-15
  • 网络出版日期:  2024-02-19
  • 刊出日期:  2016-05-29

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