Abstract: Objective Evaluation of intensity-modulated radiation therapy(IMRT) delivery quality assurance(DQA) using EDOSE software based on accelerator electronic portal imaging device (EPID). Methods Analysed the dose response uniformity correction of EPID imaging plate in different fields and the gamma pass rates about the fields; And compared the calculated parameters of the EDOSE and the Pinnacle planning station. Results The uniformities on the homogeneous region of the fields are good after who corrected by EDOSE. The gamma(γ, 3mm/3%) pass rates are in the ideal range. The volume of the organs at risk(OAR) have no statistical significance except the right lung; A part of the parameters have statistical significance. Conclusions The results of the calculation and analysis of EDOSE has a high agreement with the planning system.