光声-超声双模态成像技术的研究进展

      Advances and Challenges in Photoacoustic-Ultrasound Dual-Modality Imaging: from Hardware Innovations to Clinical Applications

      • 摘要: 光声-超声双模态联合成像技术是一种融合光声成像功能学优势与超声成像高分辨结构表征能力的新型复合成像手段。该文系统综述该技术在成像系统硬件与成像算法两个维度的研究进展:在硬件方面,新型超声换能器与多模态探头架构设计的突破性进展显著提升了组织穿透深度与信号采集效率,同时降低了系统复杂度;在成像算法层面,物理模型驱动与数据驱动方法的协同创新实现了光学特性参数与声速的精确重建,特别是基于深度学习框架的多模态特征融合与自适应优化策略,有效克服了传统方法在噪声抑制和计算效率等方面的不足。本文不仅为多模态成像技术的理论研究和临床应用提供参考,同时展望该技术在智能诊疗设备开发和精准医疗实践中的广阔应用前景。

         

        Abstract: Photoacoustic-ultrasound dual-modal imaging represents an emerging hybrid imaging technique that combines the functional advantages of photoacoustic imaging with the high-resolution structural characterization capabilities of ultrasound imaging. This article comprehensively summarizes the research status and progress from both system-level and algorithmic perspectives. In hardware development, breakthroughs in novel ultrasound transducers and multimodal probe architecture designs have significantly enhanced tissue penetration depth and signal acquisition efficiency while reducing system complexity. In terms of imaging algorithms, the synergistic innovation of physics-model-driven and data-driven approaches has achieved precise quantitative reconstruction of optical absorption parameters and sound velocity. In particular, deep learning frameworks employing multimodal feature fusion and adaptive optimization strategies have effectively addressed the limitations of conventional methods in noise suppression and computational efficiency. This article not only provides a reference for theoretical research and clinical applications of multi-modal imaging technology but also explores its broad prospects in the development of intelligent diagnostic/therapeutic devices and precision medicine practices.

         

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