基于逐口气法的人体能量代谢检测系统设计与验证

李晨东; 方伟; 王友才; 陈焱焱; 曹伟; 徐俊; 汪宇扬; 杨飞; 何子军; 孙怡宁

doi:10.12455/j.issn.1671-7104.240546

基于逐口气法的人体能量代谢检测系统设计与验证

Design and Verification of Human Energy Metabolism Detection with Breathe-by-Breathe Method

摘要

摘要:
目的设计了一种逐口气法人体呼吸气体检测系统，实现人体能量代谢实时准确测量。
方法首先，采用间接测热法实时采集人体每口呼吸气的流量和浓度信息；然后，通过特征比齐和每口气数据分割计算氧气消耗量（Q_O2）、二氧化碳产生量（Q_CO2）；最后，根据Weir公式计算人体能量代谢指标。另外，开展了与国际先进代谢测量设备MGC ULTIMA SYSTEM PFX CARDIO2的对比验证。
结果结果表明该系统测量的代谢指标均在Bland- Altman分析的一致性区间内。
结论因此，该系统与MGC测量结果一致性高，可以实时准确测量人体能量代谢，可为临床营养评估及诊疗提供数据支撑。

Abstract:
Objective In order to measure human metabolism accurately with high temporal solution, a respiratory gas analytic system was designed by breath-by-breath approach.
Methods Firstly, Indirect calorimetry was used in respiratory gas analysis that measuring signal of respiratory flow and concentration in real time. Secondly, oxygen consumption and carbon dioxide production were calculated with respiratory characteristic alignment and respiratory signal segmentation. Finally, metabolic indexes calculated according to the Weir formula. Furthermore, a controlled trials was formulated for validation comparisons with MGC ULTIMA SYSTEM PFX CARDIO2.
Results The results indicate that data points of metabolic indexes measured by this system fall within the confidence interval when compared to MGC.
Conclusions The system has high consistency with MGC measurement results, so that the system can accurately measure metabolism in real time and provide supports for clinical nutrition and therapy.

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