Abstract: In order to improve the effect of transcranial electric stimulation treatment and personalized treatment for different degrees, this paper designed a integrated four-channel EEG recording multimodal transcranial electrical stimulation system, before stimulation, stimulation, after stimulation real-time monitoring EEG signal and related characteristic analysis, facilitate doctors and researchers to resolve the current state of the brain, real-time evaluation of transcranial electrical stimulation effect, and then artificially adjust the stimulation parameters. After relevant testing and verification, the system can select four stimulation modes: TACS, TDCS, TPCS and TRNS, which can output the constant stimulation current of 0.03 mA accuracy in the range of ± 2 mA and the stimulation frequency of low frequency of 0－4 KHz (precision of 0.01 Hz) high frequency 50－100 KHz, which can obtain more accurate EEG signals under stimulation interference, which has a good market application prospect.