邮件订阅 RSS

      mDIXON-Quant技术定量T2*值及FF值对颈椎间盘退变的应用研究

      Application Research of mDIXON-Quant Quantitative T2* Values and FF Values in Cervical Intervertebral Disc Degeneration

        摘要
      • 摘要:
        目的 探讨磁共振成像改良水脂分离技术（mDIXON-Quant）定量T2*值及脂肪分数（FF）值在颈椎间盘退变程度中的临床价值。
        方法 搜集我院于2019年3月至2024年1月期间行常规颈椎MRI及mDixon-Quant检查的患者118例，测得其C2/3~C6/7椎间盘的T2*值及上、下位椎体FF值，根据普菲尔曼（Pfirrmann）标准对颈椎间盘进行退变程度分级，对不同患者的T2*值及FF值与普菲尔曼分级进行对比，用Spea rman相关性分析T2*值、FF值与普菲尔曼分级的相关性。
        结果 在颈椎间盘层面内Ⅰ级、Ⅱ级、Ⅲ级、Ⅳ级、Ⅴ级T2*值全部呈递减趋势（P<0.05），FF值在上位颈椎椎体的递减顺序为Ⅳ级、Ⅴ级、Ⅲ级、Ⅱ级、Ⅰ级（F=93.28，P＜0.05），在下位椎体的递减顺序为Ⅳ级、Ⅲ级、Ⅴ级、Ⅱ级、Ⅰ级（F=112.037，P＜0.05）。Spearman相关性分析表明颈椎间盘T2*值与普菲尔曼分级均呈负相关（P＜0.05），上、下位椎体FF值与普菲尔曼分级均为正相关（P＜0.05）。
        结论 mDIXON-Quant技术定量T2*值及FF值能够应用于颈椎间盘退行性变，对临床精确诊断、评估治疗效果等方面具有重要价值。

         

        Abstract:
        Objective To investigate the clinical value of modified water-lipid separation technique (mDIXON-Quant) T2* values and fat fraction (FF) values in evaluating the degree of cervical intervertebral disc degeneration.
        Methods A total of 118 patients who underwent routine MRI in cervical vertebra and the examination of mDixon-Quant in Fuyang People's Hospital from March 2019 to January 2024 were collected. The T2* values of C2/3 to C6/7 intervertebral discs and FF values of the upper and lower vertebral bodies were measured,and the cervical intervertebral disc degeneration was graded according to the Pfirrmann criteria. The T2* values and FF values of different patients were compared with the Pfirrmann grade,and the correlation between T2* values,FF values and Pfirrmann grade was analyzed by Spearman correlation.
        Results The T2* values of cervical intervertebral discs in grades Ⅰ, Ⅱ, Ⅲ, Ⅳ and Ⅴ all showed a decreasing trend (P＜0.05). The decreasing order of FF values in the upper cervical vertebra was IV,V,IIⅠ,Ⅱ,and Ⅰ (F=93.28, P＜0.05), and the decreasing order of FF values in the lower cervical vertebra was Ⅳ,Ⅲ,Ⅴ,Ⅱ,and Ⅰ (F=112.037, P＜0.05). Spearman correlation analysis showed that the T2* values of cervical intervertebral disc were negatively correlated with the Pfirrmann grade (P＜0.05), and the FF values of the upper and lower vertebrae were positively correlated with the Pfirrmann grade (P＜0.05).
        Conclusion The mDIXON-Quant technique can be used to quantify the T2* values and FF values of cervical intervertebral disc degeneration,and plays an important role in clinical accurate diagnosis and evaluation of treatment effect.

         

        • HTML全文
        • 参考文献(28)
        • 相关文章
        • 施引文献
      • 资源附件(0)

      /

      返回文章
      返回