中央型肺癌容积旋转调强放疗计划中设计减少肺低剂量体积的研究

张皓嘉; 张毅; 金海洁; 游士虎; 甘家应; 胡银祥

doi:10.12455/j.issn.1671-7104.240237

中央型肺癌容积旋转调强放疗计划中设计减少肺低剂量体积的研究

A Method of Reducing the Low-Dose-Area of VMAT on Lung Cancer Planning

摘要

摘要:
目的研究中央型肺癌容积旋转调强放疗计划设计中，采用不同弧段和不同形状剂量限制区设计计划，探讨有效降低肺V₅、V₁₀和MLD的方法。
方法入组病例分别设计五组计划：A组为全弧射野，B组为部分弧射野，C、D、E组为全弧射野，分别增加竖长条、半环状和三角状剂量限制区，比较各组靶区剂量学相似性及全肺V₅、V₁₀、V₂₀和MLD剂量学差异。
结果 B、C、D、E组与A组比较，靶区均匀性和适形性均降低，全肺V₅和V₁₀明显降低。C、D、E组与A组相比MLD降低。
结论采用全弧射野同时增加剂量限制区，可有效降低肺V₅、V₁₀、MLD和机器跳数。

Abstract:
Objective To study the effective method of reducing lung V₅, V₁₀ and MLD in the design of volumetric rotation-modulated radiotherapy for central lung cancer.
Methods Five group plans were designed for enrolled patients: group A was full arc field, group B was partial arc field, and groups C, D and E were full arc field. Vertical length, semi-ring and triangular dosimetry zones were added, respectively, to compare the dosimetry similarities of target areas and the dosimetry differences of lung V5, V10, V20 and MLD among the groups.
Results Compared with group A, group B, C, D and E, the uniformity and conformability of the target area were decreased, and the V5 and V10 of the whole lung were significantly decreased. The MLD of group C, D and E was lower than that of group A.
Conclusion Using full arc field and increasing dose limit zone can effectively reduce lung V5, V10, MLD and MU.

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