瓣叶修复系统的体外流体动力学性能评估

      In Vitro Hydrodynamic Performance Evaluation of Valve Repair System

      • 摘要:
        目的 针对二尖瓣反流疾病的治疗需求,该研究设计一种瓣叶修复系统,并评估其流体动力学性能。
        方法 :设计二尖瓣反流模型,将瓣叶修复系统安装到反流模型上进行脉动流试验及稳态流泄漏试验。
        结果 脉动流试验结果显示,瓣叶修复系统植入后反流量在不同心输出量及不同反向压力下比植入前降低,植入后的平均跨瓣压差小于5 mmHg;稳态流泄漏试验结果显示,随着反向压力的增高,瓣叶修复系统植入后泄漏量随之增高。
        结论 所研制的瓣叶修复系统具有良好的流体动力学性能,预示其治疗二尖瓣反流的可行性。

         

        Abstract:
        Objective In order to meet the treatment requirements of mitral regurgitation disease, this study designed a new type of valve repair system and evaluated its hydrodynamic performance.
        Methods A mitral regurgitation model was designed, and a valve repair system was loaded on the regurgitation model, and the pulsatile flow test and steady back flow leakage test were conducted.
        Results The pulsatile flow test result showed that the percentage of reflux after product implantation was lower than that before implantation under different concentric output and different reverse pressures, and the average cross valve pressure difference after implantation wss less than 5 mmHg. The steady back flow leakage test results showed that as the reverse pressure increased, the leakage amount of the valve repair system after implantation increased.
        Conclusion The developed valve repair system has good hydrodynamic performance, which indicates the feasibility of its treatment of clinical mitral regurgitation.

         

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