瓣叶修复系统的体外流体动力学性能评估

      In Vitro Hydrodynamic Performance Evaluation of Valve Repair System

      • 摘要:
        目的 针对二尖瓣反流疾病的治疗需求,该研究设计了一种瓣叶修复系统,并评估其流体动力学性能。
        方法  设计二尖瓣反流模型,将瓣叶修复系统安装到反流模型上,分别进行脉动流试验及稳态流泄漏试验。
        结果 脉动流试验结果显示,在不同心排血量及不同反向压力下,瓣叶修复系统植入后的反流量较植入前降低,且植入后的平均跨瓣压差小于5 mmHg;稳态流泄漏试验结果显示,随着反向压力的升高,瓣叶修复系统植入后的泄漏量也随之增加。
        结论 所研制的瓣叶修复系统具有良好的流体动力学性能,预示着其治疗二尖瓣反流的可行性。

         

        Abstract:
        Objective To meet the treatment requirements for mitral regurgitation disease, this study designed a novel valve repair system and evaluated its hydrodynamic performance.
        Methods A mitral regurgitation model was created. The valve repair system was loaded onto the regurgitation model, and pulsatile flow tests and steady backflow leakage tests were conducted.
        Results The pulsatile flow test results indicated that the percentage of reflux after product implantation was lower than that before implantation under different concentric outputs and reverse pressures. The average cross-valve pressure difference after implantation was less than 5 mmHg. The steady backflow leakage test results showed that as the reverse pressure increased, the leakage amount of the valve repair system after implantation also increased.
        Conclusion The developed valve repair system exhibits excellent hydrodynamic performance, suggesting the feasibility of its application in the treatment of clinical mitral regurgitation.

         

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